spinal stenosis
Methylcobalamin is a metabolite of vitamin B12 that functions as a coenzyme in the process of formation homocysteine methionine. This reaction is useful in the formation of DNA, as well as maintenance of nerve function.
Through the methylation reaction, methylcobalamin was also playing in the formation of lecithin, a protein that plays an important role in the regeneration of peripheral nerves including the formation of myelin. This process makes methylcobalamin widely used in cases of neuropathy, e.g. diabetic neuropathy, where the basic pathological process that occurs is nerve damage due to reactions that occur in conditions of hyperglycemia.
Currently, methylcobalamin Injection is formulated for the treatment of diabetes and peripheral neuropathy, auto immune disease, megaloblastic anemia, poly arthritis, spinal stenosis wood, traumatic injury, malabsorption syndrome, chronic intestinal obstruction, chronic ulcer problems, chronic fatigue syndrome and sleep disorders.
Researchers make observations in methylcobalamin Injection on the seven men and four women with symptoms of the disease diabetes. In this study uses methylcobalamin size of 2500 micrograms in 10 ml saline. Next methylcobalamin injected in patients. Treatment begins when the patient has good metabolic control, as determined by measurement of plasma glucose and hemoglobin, and repeated several times with one month interval between injections.
Three patients were treated again one year after the last intrathecal injection. Symptoms in the feet, such as paresthesia, burning pain, and weight, dramatically increase. Effects that occurred appeared within a few hours to one week and lasted from several months to four years of nerve conduction velocity did not change significantly. This research result concluded that high concentrations of methylcobalamin in spinal fluid, highly effective and safe for treating the symptoms of diabetic neuropathy.
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